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Long-term use (more than six weeks) may lead to accumulation and toxicity. [8] High daily intake over a period of months can possibly cause severe fatigue, weakness and neurological symptoms that reverse with discontinuation. [9] Some of the risks of salicylism can apply to the use of bismuth subsalicylate. [10] [11] [12]
Tums (stylized as TUMS) is an antacid made of sucrose (table sugar) and calcium carbonate (CaCO 3) manufactured by Haleon in St. Louis, Missouri, US. They are also available in a sugar-free version. It is an over-the-counter drug, available at many retail stores, including drug stores, grocery stores and mass merchandisers.
In domestic dogs, sexual maturity occurs between the ages of 6 and 12 months for both males and females, although this can be delayed until up to two years of age for some large breeds. [2] Pregnancy is possible as soon as the first estrus cycle , but breeding is not recommended prior to the second cycle. [ 3 ]
The post How Tums Antacid Became America’s Most Trusted Brand appeared first on Reader's Digest. These tiny tablets have been providing relief to overfull tummies for nearly a century, earning ...
[20] [21] [22] GonaCon has been studied in male and female dogs and cats but does not provide long-acting suppression of fertility in these species. In dogs in particular, injection site reactions preclude use of the EPA approved formulation. [23] [24] Zona pellucida vaccines are targeted at females and do not suppress fertility in dogs or cats ...
Dogs reach puberty between 6 and 24 months old, at which age female dogs will start having an estrous cycle. There are four stages of estrous: proestrus, estrus, diestrus, and anestrus. A dog in estrus, also known as being "in heat", can become pregnant during this 3- to 21-day period. [3]
It is not essential for a female dog to either experience a heat cycle or have puppies before spaying, and likewise, a male dog does not need the experience of mating before neutering. Female cats and dogs are seven times more likely to develop mammary tumors if they are not spayed before their first heat cycle . [ 77 ]
A female dog is usually diestrous (goes into heat typically twice per year), although some breeds typically have one or three cycles per year. The proestrus is relatively long at 5 to 9 days, while the estrus may last 4 to 13 days, with a diestrus of 60 days followed by about 90 to 150 days of anestrus.