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Sulfasalazine metabolizes to sulfapyridine. Serum levels should be monitored every three months, and more frequently at the outset. Serum levels above 50 μg/L are associated with side effects. In rare cases, sulfasalazine can cause severe depression in young males. It can also cause oligospermia and temporary infertility.
Common side-effects include headache, nausea, abdominal pain, and fever. [1] Serious side-effects may include pericarditis, liver problems, and kidney problems. [1] [12] Use in pregnancy and breastfeeding appears safe. [12] In people with a sulfa allergy certain formulations may result in problems. [1] Mesalazine is an aminosalicylate and anti ...
In some cases, sulfasalazine can exacerbate ulcerative colitis resulting in diarrhea, abdominal cramps and discomfort. In the intestine sulfasalazine is converted to 5-ASA and sulfapyridine, which is responsible for some of its side-effects, and which should be monitored in patients taking sulfasalazine.
In 1977, it was shown that 5-aminosalicylic acid (5-ASA, mesalazine/mesalamine) was the therapeutically active component in sulfasalazine. [111] Many 5-ASA drugs have been developed with the aim of delivering the active compound to the large intestine to maintain therapeutic efficacy but with reduction of the side effects associated with the ...
An American Airlines regional jet went down in the Potomac River near Washington, D.C.'s Ronald Reagan Washington National Airport after colliding with a U.S. Army Black Hawk helicopter on ...
Sulfasalazine; Mesalazine (5-Aminosalicylic acid) Side effects may include abdominal pain, diarrhea, headaches, and nausea. [1] References This page was last edited ...
A Brooklyn principal who lives on Long Island uses the address of a parent at her Brownsville job to send her own daughter to a higher-performing school 10 minutes from where she works, The Post ...
The side effects of semaglutide are quite similar to those of tirzepatide, as the drugs work similarly. Both target the GLP-1 receptor, but tirzepatide also targets the insulinotropic polypeptide ...
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