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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Poliovirus causes Polio, or Poliomyelitis, which is a disabling and life-threatening disease that causes paresthesia, meningitis and permanent paralysis. [16] Symptoms can include sore throat, fever, tiredness, nausea, headache and stomach pain although 72% of those that get infected will not display visible symptoms. [ 16 ]
Polio eradication, the goal of permanent global cessation of circulation of the poliovirus and hence elimination of the poliomyelitis (polio) it causes, is the aim of a multinational public health effort begun in 1988, led by the World Health Organization (WHO), the United Nations Children's Fund (UNICEF) and the Rotary Foundation. [55]
Sublingual (abbreviated SL), from the Latin for "under the tongue", refers to the pharmacological route of administration by which substances diffuse into the blood through tissues under the tongue.
A child receives oral polio vaccine during a 2002 campaign to immunize children in India. Poliovirus. Polio eradication, the goal of permanent global cessation of circulation of the poliovirus and hence elimination of the poliomyelitis (polio) it causes, is the aim of a multinational public health effort begun in 1988, led by the World Health Organization (WHO), the United Nations Children's ...
The second vaccine, an oral polio vaccine (OPV), is a live-attenuated vaccine, produced by the passage of the virus through non-human cells at a sub-physiological temperature. The passage of virus produces mutations within the viral genome, and hinders the virus's ability to infect nervous tissue. [6]
The other additions in UIP through the way are inactivated polio vaccine (IPV), rotavirus vaccine (RVV), Measles-Rubella vaccine (MR). Four new vaccines have been introduced into the country's Universal Immunisation Programme (UIP), including injectable polio vaccine, an adult vaccine against Japanese Encephalitis and Pneumococcal Conjugate ...
Neurotropic viruses that cause infection include Japanese Encephalitis, Venezuelan Equine Encephalitis, and California encephalitis viruses; polio, coxsackie, echo, mumps, measles, influenza and rabies, as well as diseases caused by members of the family Herpesviridae such as herpes simplex, varicella-zoster, Epstein–Barr, cytomegalovirus and HHV-6 viruses. [2]