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Nelson's syndrome is a disorder that occurs in about one in four patients who have had both adrenal glands removed to treat Cushing's disease. [1] In patients with pre-existing adrenocorticotropic hormone ()-secreting pituitary adenomas, loss of adrenal feedback following bilateral adrenalectomy can trigger the rapid growth of the tumor, leading to visual symptoms (e.g. bitemporal hemianopsia ...
Alfredo Quiñones-Hinojosa's Seminar: "Brain Tumors and Stem Cells" An 'American' Success Story, May 19, 2007; The Amazing Doctor Q, February 11, 2009; Once a migrant worker, today he’s a brain surgeon, updated 7/23/2008 9:51:16 AM ET; From Farmhand to Brain Surgeon Posted 07.01.08; The American Dream: Dr. Quiñones' Incredible Journey, June ...
David S. Baskin is a neurosurgeon who currently works at Houston Methodist Hospital as the Vice Chairman of the Department of Neurosurgery, the Director of the Residency Training program, and the Director of the Kenneth R. Peak Brain & Pituitary Tumor Center, and is also a professor of neurosurgery at Weill Cornell Medical College.
Pituitary adenomas are tumors that occur in the pituitary gland. Most pituitary tumors are benign, approximately 35% are invasive and just 0.1% to 0.2% are carcinomas. [1] Pituitary adenomas represent from 10% to 25% of all intracranial neoplasms, with an estimated prevalence rate in the general population of approximately 17%. [1] [2]
Other hormone-secreting cells of the pituitary undergo rapid growth in pregnant women as well, which contribute to the gland's enlargement. [10] The anterior pituitary is supplied by a low pressure portal venous system. [15] The anterior pituitary is more commonly affected in Sheehan's syndrome because of the structure of the portal venous system.
Autoimmune hypophysitis (or lymphocytic hypophysitis), inflammation of the pituitary gland due to autoimmunity. Nelson's syndrome, may occur after surgical removal of both adrenal glands, an out-dated method of treating Cushing's disease. Pituitary tumour, a tumor of the pituitary gland. Pituitary adenoma, a noncancerous tumor of the pituitary ...
Since pharmacological therapy has had little effect on these tumors, a trans-sphenoidal surgery to remove part of the pituitary gland is the first treatment option. [5] TSH-secreting: Another rare condition only resulting in 1% of pituitary surgeries is a result of the increase in the secretion of the thyroid-stimulating hormone.
A CT or MRI of the pituitary may also show the ACTH-secreting tumor if present. However, in 40% of Cushing's disease patients MRI is unable to detect a tumor. [8] In one study of 261 patients with confirmed pituitary Cushing's disease, only 48% of pituitary lesions were identified using MRI prior to surgery.
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