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Cannabis is a known risk factor for developing psychosis that can progress to schizophrenia but this is the first time researchers have found brain-level changes in an at-risk population in real time.
The temporal relationship between cannabis and psychosis was reviewed in 2014, and the authors proposed that "[b]ecause longitudinal work indicates that cannabis use precedes psychotic symptoms, it seems reasonable to assume a causal relationship" between cannabis and psychosis, but that "more work is needed to address the possibility of gene ...
A 2019 meta-analysis found that 34% of people with cannabis-induced psychosis transitioned to schizophrenia. This was found to be comparatively higher than hallucinogens (26%) and amphetamines (22%). [46] To screen for cannabis-related problems, several methods are used.
There is evidence that long-term use of cannabis increases the risk of psychosis, regardless of confounding factors, and particularly for people who have genetic risk factors. [110] A 2019 meta-analysis found that 34% of people with cannabis-induced psychosis transitioned to schizophrenia.
As many as half of people with cannabis-induced psychosis may go on to develop either schizophrenia or bipolar disorder, research suggests. Young adults and teenagers should be especially ...
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In European-American women, sexual and physical abuse, as well as major depressive disorder (MDD) predicted age of cannabis initiation, with development of a CUD being predicting more specifically by MDD and physical abuse. [13] Those with sexual trauma who initiate cannabis use prior to the age of 16, are also more likely to develop psychosis ...
There was no association between cannabis use and psychotic disorders in people ages 20 to 33. ... yet fully characterized — where there’s a window of time where cannabis use may increase the ...