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Cannabis is a known risk factor for developing psychosis that can progress to schizophrenia but this is the first time researchers have found brain-level changes in an at-risk population in real time.
As of 2017 there was clear evidence that long-term use of cannabis increases the risk of psychosis, regardless of confounding factors, and particularly for people who have genetic risk factors, [43] but see previous section. Even in those with no family history of psychosis, the administration of pure THC in clinical settings has been ...
As many as half of people with cannabis-induced psychosis may go on to develop either schizophrenia or bipolar disorder, research suggests. Young adults and teenagers should be especially ...
The strength of cannabis used, with higher THC content conferring a heightened risk, is also thought to be a risk factor. [25] Concomitant alcohol or tobacco use, a history of adverse childhood experiences , depression or other psychiatric disorders, stressful life events and parental cannabis use may also increase the risk of developing ...
There is evidence that long-term use of cannabis increases the risk of psychosis, regardless of confounding factors, and particularly for people who have genetic risk factors. [110] A 2019 meta-analysis found that 34% of people with cannabis-induced psychosis transitioned to schizophrenia.
The study, led by researchers from the University of Toronto, found an 11 times higher risk of developing a psychotic disorder among teenagers who used cannabis compared with those who did not.
Most addictive substances can induce psychosis. A diagnosis of substance-induced psychosis is made if symptoms persist after drug use or intoxication has ended. [120] A number of substance-induced psychoses have the potential to transition to schizophrenia, most notably cannabis-induced psychosis.
THC is the main psychoactive substance in cannabis. For premium support please call: 800-290-4726 more ways to reach us