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2. Colombian family's genes offer new clue to delaying onset of ...

   www.aol.com/news/colombian-familys-genes-offer...

   Alzheimer’s usually is a disease of people over age 65 and while simply getting older is the main risk, the APOE gene has long been known to play some role. It comes in three main varieties.

3. Apolipoprotein E - Wikipedia

   en.wikipedia.org/wiki/Apolipoprotein_E

   Indeed, the apolipoprotein ε4 isoform is more protective against cognitive decline than other isoforms in some cases, [58] so caution is advised before making determinant statements about the influence of APOE polymorphisms on cognition, development of Alzheimer's disease, cardiovascular disease, telomere shortening, etc. Many of the studies ...

4. Carlos Cruchaga - Wikipedia

   en.wikipedia.org/wiki/Carlos_Cruchaga

   Cruchaga and his lab generates and analyze human multi-omic (genetic, epigenomic, transcriptomic, proteomic, metabolomic and lipidomic) data generated from well clinically-characterized cohorts in order to identify novel genes and pathways implicated on neurodegenerative disease, mainly Alzheimer's and Parkinson's disease, to identify novel molecular biomarkers and druggable targets.

5. Alzheimer's disease - Wikipedia

   en.wikipedia.org/wiki/Alzheimer's_disease

   [57] [58] Genetic models in 2020 predict Alzheimer's disease with 90% accuracy. [59] Most cases of Alzheimer's are not familial, and so they are termed sporadic Alzheimer's disease. [60] Of the cases of sporadic Alzheimer's disease, most are classified as late onset where they are developed after the age of 65 years. [61]

6. Heart diseases raise dementia risk: Could a common blood ...

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   “Some of our co-authors had previously shown that a rare genetic mutation in the APOE gene is actually very protective against Alzheimer’s disease, and that this had something to do with ...

7. A subset of Alzheimer's cases may be caused by two ... - AOL

   www.aol.com/news/subset-alzheimers-cases-may...

   Some carry APOE2, which provides some protection against Alzheimer’s. APOE4 has long been labeled the biggest genetic risk factor for late-in-life Alzheimer’s, with two copies risker than one.