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Two-pore channels (TPCs) are eukaryotic intracellular voltage-gated and ligand gated cation selective ion channels. [1] There are two known paralogs in the human genome, TPC1s and TPC2s. [ 2 ] In humans, TPC1s are sodium selective and TPC2s conduct sodium ions, calcium ions and possibly hydrogen ions.
The channel was launched as an "original channel", which meant that YouTube funded the channel. [3] [4] The show's initial grant was projected to expire in 2014, and in response, on September 12, 2013, SciShow joined the viewer-funding site Subbable, created in part by Green. [5] [6] In 2014, the channel landed a national advertisement deal ...
Inside view of a negative pressure isolation chamber for patients with contagious diseases. Schematic of a network of rooms where air (shown in blue) flows in one direction from the corridor into the negative pressure room (green). Exhaust air is safely removed from the area through a ventilation system.
Anion Channels: they exhibit a significant permeability for negative ions, and are not predominant as cation MS. They have a large conductance range (> 300pS). Non Selective ion channels: As the name indicates, they do not differentiate between positive and negative channels those are more common to Archaea and Bacteria, but rarely found in ...
In the life sciences, mass flow, also known as mass transfer and bulk flow, is the movement of fluids down a pressure or temperature gradient. [1] As such, mass flow is a subject of study in both fluid dynamics and biology. Examples of mass flow include blood circulation and transport of water in vascular plant tissues. Mass flow is not to be ...
Microfluidics is the study and design of the control or transport of small volumes of fluid flow through porous material or narrow channels for a variety of applications (e.g. mixing, separations). Capillary pressure is one of many geometry-related characteristics that can be altered in a microfluidic device to optimize a certain process.
In this process, a mechanically gated ion channel makes it possible for sound, pressure, or movement to cause a change in the excitability of specialized sensory cells and sensory neurons. [9] The stimulation of a mechanoreceptor causes mechanically sensitive ion channels to open and produce a transduction current that changes the membrane ...
The tight junctions have a net negative charge, and are believed to preferentially transport positively charged molecules. Tight junctions in the intestinal epithelium are also known to be size-selective, such that large molecules (with molecular radii greater than about 4.5 Å ) are excluded.