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Many side effects and adverse drug reactions have been reported with oral terbinafine hydrochloride, [13] [14] possibly due to its extensive biodistribution and the often extended durations involved in antifungal treatment (longer than two months). A comprehensive list of adverse events associated with terbinafine use includes:
Most infections can be treated with topical antifungal medication. Rarely, more extensive or long-standing infections may require treatment with oral antifungals. The infection will still be contagious between 24 and 48 hours of the first treatment. The ringworm should go away within 4–6 weeks after using effective treatment.
Ringworm can also be acquired from other animals such as horses, pigs, ferrets, and cows. The fungus can also be spread by touching inanimate objects like personal care products, bed linen, combs, athletic gear, or hair brushes contaminated by an affected person. [3] Individuals at high risk of acquiring ringworm include those who: [citation ...
The infection, which can take months to clear up even with treatment, has been increasingly diagnosed throughout Europe. Highly contagious form of sexually transmitted ringworm reported in the US ...
Dermatophytosis, also known as tinea and ringworm, is a fungal infection of the skin [2] (a dermatomycosis), that may affect skin, hair, and nails. [1] Typically it results in a red, itchy, scaly, circular rash. [ 1 ]
The side effects of oral treatment are significant and people without an infection should not take these drugs. [36] Azoles are the group of antifungals which act on the cell membrane of fungi. They inhibit the enzyme 14-alpha-sterol demethylase, a microsomal CYP, which is required for the biosynthesis of ergosterol for the cytoplasmic membrane.
Treatment of tinea capitis requires an oral antifungal agent; griseofulvin is the most commonly used drug, but other newer antimycotic drugs, such as terbinafine, itraconazole, and fluconazole have started to gain acceptance.
Kerion or kerion celsi is an acute inflammatory process which is the result of the host's response to a fungal ringworm infection of the hair follicles of the scalp (occasionally the beard) that can be accompanied by secondary bacterial infection(s). It usually appears as raised, spongy lesions, and typically occurs in children. [1]
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