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  2. Discovery and development of direct thrombin inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    In October 2010 the US FDA approved dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF). [6] [10] Many pharmaceutical companies have attempted to develop orally bioavailable DTI drugs but dabigatran etexilate is the only one to reach the market. [9]

  3. Direct thrombin inhibitor - Wikipedia

    en.wikipedia.org/wiki/Direct_thrombin_inhibitor

    Dabigatran is an oral direct thrombin inhibitor. Dabigatran (Pradaxa) was found to be noninferior to Warfarin in prevention of ischemic stroke, as well as intracranial hemorrhage risk and overall mortality for non-valvular atrial fibrillation according to the RE-LY trial. [9]

  4. Dabigatran - Wikipedia

    en.wikipedia.org/wiki/Dabigatran

    Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. [ 6 ] [ 7 ] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [ 6 ]

  5. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    [4] [5] [6] They are commonly prescribed to treat and prevent blood clots in veins, prevent stroke and embolism in people with non-valvular atrial fibrillation (AF) who have other risk factors, and prevent blood clots after routine knee and hip replacement surgery. [2] [3] [7]

  6. Children's Health Act - Wikipedia

    en.wikipedia.org/wiki/Children's_Health_Act

    The Children's Health Act of 2000 (Pub. L. 106–310 (text), 114 Stat. 1101, enacted October 17, 2000), signed by President Clinton on October 17, 2000, was brought into law to conduct a study focusing on children from before conception to 21 years of age. [1]

  7. CARE Act - Wikipedia

    en.wikipedia.org/wiki/CARE_Act

    To enforce child abuse and neglect laws, including laws protecting against child sexual abuse To promote programs designed to prevent child abuse and neglect To establish or support cooperative programs between law enforcement and media organizations to collect, record, retain, and disseminate information useful in the identification and ...

  8. Provisions of the Affordable Care Act - Wikipedia

    en.wikipedia.org/wiki/Provisions_of_the...

    The Community Living Assistance Services and Supports Act (CLASS Act) provision would have created a voluntary long-term care insurance program, but in October 2011 the Department of Health and Human Services announced that the provision was unworkable and would be dropped. [123] [124] The CLASS Act was repealed January 1, 2013. [125]

  9. Antiplatelet drug - Wikipedia

    en.wikipedia.org/wiki/Antiplatelet_drug

    Antiplatelet drugs are widely used in primary and secondary prevention of thrombotic disease, especially myocardial infarction and ischemic stroke. [1] Antiplatelet therapy with one or more of these drugs decreases the ability of blood clots to form by interfering with the platelet activation process in primary hemostasis. Antiplatelet drugs ...

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