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Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [3] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Cetacaine is a topical anesthetic that contains the active ingredients benzocaine (14%), butamben (2%), and tetracaine hydrochloride (2%). Cetacaine also contains small amounts of benzalkonium chloride at 0.5% and 0.005% of cetyl dimethyl ethyl ammonium bromide all in a bland water-soluble base. [1]
Polymethylsiloxane polyhydrate (PMSPH), or methylsilicic acid hydrogel (brand name — Enterosgel), is an enterosorbent [1] used for binding and removing various toxic substances, infectious agents and metabolites from the gastrointestinal tract.
[13]: 69–75 Felix Hoffmann (or Arthur Eichengrün) of Bayer was the first to produce acetylsalicylic acid in a pure, stable form in 1897. [14] By 1899, Bayer had dubbed this drug Aspirin and was selling it globally. [15]: 27 Aspirin is available without medical prescription as a proprietary or generic medication [10] in most jurisdictions.
Merbromin (marketed as Mercurochrome, Merbromine, Mercurocol, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept and Cinfacromin) is an organomercuric disodium salt compound used as a topical antiseptic for minor cuts and scrapes and as a biological dye.
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin, as the phosphate, an antibiotic; and benzoyl peroxide, an antiseptic. [7] Common side effects include peeling, itching, and dryness of the skin where the gel was ...
The three primary enzymes in Biotène were glucose oxidase, lactoperoxidase, and lysozyme. [7] These enzymes, through their antibacterial and healing properties, create natural protection within the oral cavity, balancing and boosting an individual's salivary defenses.
Excedrin Migraine continued the trend of marketing pain products for specific types of pain, becoming the first migraine headache medication available to consumers without a prescription, [9] even though it has identical active ingredients to the regular Excedrin Extra Strength product, 250 mg acetaminophen, 250 mg aspirin, and 65 mg caffeine ...