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In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
Grade A: One or more mucosal breaks < 5 mm in maximal length Grade B: One or more mucosal breaks > 5mm, but without continuity across mucosal folds: Grade C: Mucosal breaks continuous between ≥ 2 mucosal folds but involving less than 75% of the esophageal circumference Grade D: Mucosal breaks involving more than 75% of esophageal circumference
Barium X-ray examinations are useful tools for the study of appearance and function of the parts of the gastrointestinal tract. They are used to diagnose and monitor esophageal reflux, dysphagia, hiatus hernia, strictures, diverticula, pyloric stenosis, gastritis, enteritis, volvulus, varices, ulcers, tumors, and gastrointestinal dysmotility, as well as to detect foreign bodies.
Esophageal webs are associated with bullous diseases (such as epidermolysis bullosa, pemphigus, and bullous pemphigoid), with graft versus host disease involving the esophagus, and with celiac disease. [5] Esophageal webs are more common in white individuals and in women (with a ratio of 2:1).
Laryngopharyngeal reflux (LPR) or laryngopharyngeal reflux disease (LPRD) is the retrograde flow of gastric contents into the larynx, oropharynx and/or the nasopharynx. [4] [5] LPR causes respiratory symptoms such as cough and wheezing [6] and is often associated with head and neck complaints such as dysphonia, globus pharyngis, and dysphagia. [7]
The esophageal gland or pouch is a common feature in so-called basal gastropod clades, including Patelloidea, Vetigastropoda, Cocculiniformia, Neritimorpha and Neomphalina. [ 4 ] The size of the esophageal gland of the scaly-foot gastropod Chrysomallon squamiferum (family Peltospiridae within Neomphalina) is about two orders of magnitude over ...
Micrograph of an esophageal biopsy showing herpes eosphagitis, with the characteristic nuclear changes (nuclear moulding, chromatin clumping at the nuclear membrane (margination) and multinucleation). H&E stain. Upper Endoscopy often reveals ulcers throughout the esophagus with intervening normal-appearing mucosa.
In order to open the stricture, a surgeon can insert a bougie – a weighted tube used to dilate the constricted areas in the esophagus. [3] It can sometimes be treated with other medications. For example, an H2 antagonist (e.g. ranitidine ) or a proton-pump inhibitor (e.g. omeprazole ) can treat underlying acid reflux disease.