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Some vitamins are toxic in high doses [69] and nearly all (with the possible exception of Vitamin C [84]) will cause adverse effects given high levels of overdosing for prolonged periods as recommended by orthomolecular practitioners. [10] Forgoing medical care in favor of orthomolecular treatments can lead to adverse health outcomes. [6]
Megavitamin therapy is the use of large doses of vitamins, often many times greater than the recommended dietary allowance (RDA) in the attempt to prevent or treat diseases. Megavitamin therapy is typically used in alternative medicine by practitioners who call their approach orthomolecular medicine . [ 1 ]
Working in Saskatchewan with Humphry Osmond (who coined the term "psychedelic"), Hoffer and other scientists sought to find medicinal uses for hallucinogenic drugs. [16] Part of the research involved Hoffer, Osmond and their wives consuming LSD in an effort to become better acquainted with, and better understand its effects, later joined by other experimenters and their wives. [17]
The Recommended Dietary Allowance (RDA) for vitamin B12 is 0.9-2.4 μg/day, while the estimated average requirement in the U.S. and Canada is 0.7-2 μg/day. Elderly individuals with plasma vitamin B12 levels below 148 pmol/L are considered severely deficient, and those with levels between 148 and 221 pmol/L are marginally deficient.
Dr. Michael Roizen, the chief wellness officer at Cleveland Clinic who has written books on longevity, is 78 years old but told Business Insider he had a "biological age" of 57.6. (It's important ...
Orthomolecular-based megadose recommendations for vitamin C are based mainly on theoretical speculation and observational studies, such as those published by Ferd R. Klenner from the 1940s through the 1970s. There is a strong advocacy movement for very high doses of vitamin C, yet there is an absence of large-scale, formal trials in the 10 to ...
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