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A Mongolian spot, also known as slate grey nevus or congenital dermal melanocytosis, is a benign, flat, congenital birthmark with wavy borders and an irregular shape. In 1883, it was described and named after Mongolians by Erwin Bälz, a German anthropologist based in Japan, who erroneously believed it to be most prevalent among his Mongolian patients.
Several birthmark types are part of the group of skin lesions known as nevi or naevi, which is Latin for "birthmarks". Birthmarks occur as a result of a localized imbalance in factors controlling the development and migration of skin cells. In addition, it is known that vascular birthmarks are not hereditary. [2] [3]
Depending on the location of the birthmark and other associated symptoms, a physician may choose to order a measurement of intraocular pressure or X-ray of the skull. An MRI of the brain may be performed (under anesthesia) on infants who have a port-wine stain in the head area in order to check for signs of Sturge–Weber syndrome. [2]
The birthmark is a Mongolian spot and is apparently homozygous recessive. Nearly all Samoan infants were born with this mark, but any ancestry outside of Samoa, however slight, results in the infant not showing the mark. The birthmark is now very rare in Samoa, and can only be found occasionally on remote islands to the west.
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Naegeli–Franceschetti–Jadassohn syndrome (NFJS), also known as chromatophore nevus of Naegeli and Naegeli syndrome, [1] [2] is a rare autosomal dominant [3] form of ectodermal dysplasia, characterized by reticular skin pigmentation, diminished function of the sweat glands, the absence of teeth and hyperkeratosis of the palms and soles.
It should not be confused with Mongolian spot, which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among Caucasian people. [6] Nevus of Ota may not be congenital, and may appear during puberty.
AKRON - The photo of Jenna and Jillian Thistlethwaite holding hands just after birth drew worldwide attention. Six months later, the twins are thriving and the global attention has died down, but ...