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By the late 1990s, dengue was the most important mosquito-borne disease affecting humans after malaria, with around 40 million cases of dengue fever and several hundred thousand cases of dengue hemorrhagic fever each year. Significant outbreaks of dengue fever tend to occur every five or six months.
The plaque reduction neutralization test is used to quantify the titer of neutralizing antibody for a virus. [1] [2]The serum sample or solution of antibody to be tested is diluted and mixed with a viral suspension.
In Bangladesh's ongoing 2023 dengue epidemic season, the country has been witnessing the deadliest outbreak of dengue fever ever since the first outbreak in Bangladesh in 2000. [ 1 ] [ 2 ] [ 3 ] As of 31 December 2023, the Directorate General of Health Services (DGHS) has reported 321,179 hospitalizations and 1,705 deaths due to the Aedes ...
Over the last twenty years, there has been a geographic spread of the disease. Dengue incidence rates have risen sharply within urban areas which have recently become endemic hot spots for the disease. [57] The recent spread of Dengue can also be attributed to rapid population growth, increased coagulation in urban areas, and global travel.
In the 2023 dengue outbreak in ... by the heat as summer of 2023 was recorded as the highest temperature in 100,000 years. [2] ... terms may apply.
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
The Expanded Program on Immunization (EPI) in the Philippines began in 1976 [1] through Presidential Decree No. 996 signed by President Ferdinand Marcos. [2] And, in 1986, made a response to the Universal Child Immunization goal. The four major strategies include: [3]
The infecting serotype was dengue virus-1. This epidemic was followed by outbreaks in 1981 and 1997. In those outbreaks; dengue virus-2 was the infecting serotype. 205 cases of dengue hemorrhagic fever and dengue shock syndrome occurred during the 1997 outbreak, all in people older than 15 years.