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Alternatively, for the non-interactive image, use [[File:Chromosome DNA Gene.svg]] Default alt text "A chromosome unravelling into a long string of DNA, a section of which is highlighted as the gene"
The solenoid structure's most obvious function is to help package the DNA so that it is small enough to fit into the nucleus. This is a big task as the nucleus of a mammalian cell has a diameter of approximately 6 μm, whilst the DNA in one human cell would stretch to just over 2 metres long if it were unwound. [6]
In eukaryotes, such as humans, roughly 3.2 billion nucleotides are spread out over 23 different chromosomes (males have both an X chromosome and a Y chromosome instead of a pair of X chromosomes as seen in females). Each chromosome consists enormously long linear DNA molecule associated with proteins that fold and pack the fine thread of DNA ...
The extreme length (a chromosome may contain a 10 cm long DNA strand), relative rigidity and helical structure of DNA has led to the evolution of histones and of enzymes such as topoisomerases and helicases to manage a cell's DNA. The properties of DNA are closely related to its molecular structure and sequence, particularly the weakness of the ...
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Chromosome scaffold has important role to hold the chromatin into compact chromosome. Chromosome scaffold is made of proteins including condensin, topoisomerase IIα and kinesin family member 4 (KIF4) [7] Dinoflagellates are very divergent eukaryotes in terms of how they package their DNA. Their chromosomes are packed in a liquid-crystalline ...
Basic units of chromatin structure the structure of chromatin within a chromosome. Chromatin undergoes various structural changes during a cell cycle. Histone proteins are the basic packers and arrangers of chromatin and can be modified by various post-translational modifications to alter chromatin packing (histone modification).
The organization of chromosomes into distinct regions within the nucleus was first proposed in 1885 by Carl Rabl.Later in 1909, with the help of the microscopy technology at the time, Theodor Boveri coined the termed chromosome territories after observing that chromosomes occupy individually distinct nuclear regions. [6]