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Calciphylaxis, also known as calcific uremic arteriolopathy (CUA) or “Grey Scale”, is a rare syndrome characterized by painful skin lesions.The pathogenesis of calciphylaxis is unclear but believed to involve calcification of the small blood vessels located within the fatty tissue and deeper layers of the skin, blood clots, and eventual death of skin cells due to lack of blood flow. [1]
The causes listed are relatively immediate medical causes, but the ultimate cause of death might be described differently. For example, tobacco smoking often causes lung disease or cancer, and alcohol use disorder can cause liver failure or a motor vehicle accident.
Vital statistics generally distinguish specific injuries and diseases as cause of death, from general categories like homicide, accident, and death by natural causes as manner of death. Both are listed in this category, as are both proximal and root causes of death. An injury that could be fatal is called major trauma; see also Category:Injuries.
Calciphylaxis, though uncommon, can develop in patients with tertiary hyperparathyroidism. The product of elevated calcium and phosphate, forming crystal structures, that are then deposited in blood vessels. These crystals cause an inflammatory response and can lead to the occlusion of smaller vessels.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
In law, medicine, and statistics, cause of death is an official determination of the conditions resulting in a human's death, which may be recorded on a death certificate. A cause of death is determined by a medical examiner. In rare cases, an autopsy needs to be performed by a pathologist. The cause of death is a specific disease or injury, in ...
Coronary artery disease is the leading cause of death for both males and females and accounts for approximately 600,000 deaths in the United States every year. [139] According to present trends in the United States, half of healthy 40-year-old males will develop CAD in the future, and one in three healthy 40-year-old females. [140]
Cadaveric spasm is seen in cases of drowning victims when grass, weeds, roots or other materials are clutched, and provides evidence of life at the time of entry into the water. Cadaveric spasm often crystallizes the last activity one did before death and is therefore significant in forensic investigations, e.g. holding onto a knife tightly. [4]