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William Bradley Coley (January 12, 1862 – April 16, 1936) was an American bone surgeon and cancer researcher best known for his early contributions to the study of cancer immunotherapy, specifically causing infection as a way to fight cancer, a practice used as far back as 1550 BC. [1]
1900 – Swedish Dr. Stenbeck cures a skin cancer with small doses of radiation [4]; 1920s – Dr. William B. Coley's immunotherapy treatment, regressed tumors in hundreds of cases, the success of Coley's Toxins attracted heavy resistance from his rival and supervisor, Dr. James Ewing, who was an ardent supporter of radiation therapy for cancer.
1893 – Use of live bacteria and bacterial lysates to treat tumors – "Coley's Toxins", based on Busch and Fehleisen experiences (William B. Coley) 1894 – Bacteriolysis (Richard Pfeiffer) 1896 – An antibacterial, heat-labile serum component is described (Jules Bordet) 1900 – Antibody formation theory (Paul Ehrlich)
The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology is presented annually by the Cancer Research Institute, to scientists [1] who have made outstanding achievements in the fields of basic and tumor immunology and whose work has deepened our understanding of the immune system's response to disease, including cancer.
Here are nine of some of the most significant archaeological discoveries in history that changed what humans know about our origins and culture through time. Pompeii and Herculaneum gave a glimpse ...
CRI was created in honor of Nauts' father, William Coley (1862–1936), an American orthopedic surgeon and a pioneer of cancer immunotherapy. Grounded in Dr. Coley’s pioneering work, the Cancer Research Institute focuses on immunological treatments for cancer, both as a single treatment approach as well as a complement and enhancer to ...
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Coley's toxins (also called Coley's toxin, [1] Coley's vaccine, [2] Coley vaccine, Coley's fluid or mixed bacterial vaccine) is a mixture containing toxins filtered from killed bacteria of species Streptococcus pyogenes and Serratia marcescens, named after William Coley, a surgical oncologist at the Hospital for Special Surgery who developed the mixture in the late 19th century as a treatment ...