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Mupirocin, sold under the brand name Bactroban among others, is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis. [ 5 ] [ 6 ] [ 7 ] It may also be used to get rid of methicillin-resistant S. aureus (MRSA) when present in the nose without symptoms. [ 6 ]
Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis: Discolored urine, headache, metallic taste, nausea; alcohol is contraindicated: Produces toxic free radicals that disrupt DNA and proteins. This non-specific mechanism is responsible for its activity against a variety of bacteria, amoebae, and protozoa ...
By culturing P. fluorescens, mupirocin (an antibiotic) can be produced, which has been found to be useful in treating skin, ear, and eye disorders. [23] Mupirocin free acid and its salts and esters are agents currently used in creams, ointments, and sprays as a treatment of methicillin-resistant Staphylococcus aureus infection.
Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [ 79 ] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection.
Photosensitizers can be incorporated into polymers resulting in materials that can kill microbes on their surfaces when activated by visible light. [37] [38] Such polymers have been shown to be effective in killing bacteria in a clinical environment. [39]
Detailedly, broad-spectrum antibiotics can kill or inhibit a wide range of microorganisms; extended-spectrum antibiotic can kill or inhibit Gram positive bacteria and some Gram negative bacteria; narrow-spectrum antibiotic can only kill or inhibit limited species of bacteria. [1] [2] [3]
Treatments for pitted keratolysis typically involve antibiotics aimed at eliminating K. sedentarius and associated bacteria. Commonly prescribed antibiotics include erythromycin, mupirocin, and clindamycin. Preventive measures include keeping the feet dry and using absorbent cotton socks to minimize moisture accumulation. [11]
Thus, neomycin kills bacteria as a result of irregular protein production in the bacterial cell. When the cell can no longer produce the correct proteins, its membrane becomes damaged. [23] As a result of damaged membrane, the affected bacterial cells die, and the infection is prevented or limited. [medical citation needed]
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