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Treatments that work for one species of Leishmania may not work for another; therefore, it is recommended that the exact species be identified prior to initiating treatment. Unfortunately, leishmaniasis is an orphan disease in developed nations, and almost all the current treatment options are toxic with significant side effects. [18]
Frequent hand-washing is the usual cause, but it is also part of normal ageing. [3] Manicures, nail polish and remover, nail biting, and repeated trauma such as typing, can contribute to nail splitting. [1] Dehydration likely plays a role. [3] Nutritional deficiencies that can result in nail splitting include iron, selenium, and zinc. [1]
Smith–Magenis syndrome (SMS), also known as 17p- syndrome, is a microdeletion syndrome characterized by an abnormality in the short (p) arm of chromosome 17. [1] It has features including intellectual disability, facial abnormalities, difficulty sleeping, and numerous behavioral problems such as self-harm.
Generally, treatment options are limited. [4] Injecting the lesion with cidofovir or applying imiquimod has been tried. [4] It is sometimes necessary to cut them out. [4] The vaccine used in sheep to prevent orf is live and has been known to cause disease in humans. [4] The disease is endemic in livestock herds worldwide. [2]
Bite wounds can cause a number of signs and symptoms Generalized tissue damage due to tearing and scratching; Serious hemorrhage if major blood vessels are pierced; Infection by bacteria or other pathogens, including rabies; Introduction of venom into the wound by venomous animals such as some snakes
Terry's nails is a physical condition in which a person's fingernails or toenails [1]: 659 appear white with a characteristic "ground glass" appearance without any lunula. [2]
Onychotillomania is a compulsive behavior in which a person picks constantly at the nails or tries to tear them off. [1] It is not the same as onychophagia , where the nails are bitten or chewed, or dermatillomania , where skin is bitten or scratched.
Nail psoriasis can affect the fingernails and toenails. It may cause thickening of the nails with areas of pitting, ridges, irregular contour, and even raising of the nail from the nail bed. [18] Squamous-cell carcinoma is mainly cancer of the skin, but can also affect the nail bed. It is a rare malignant subungual tumor subject to misdiagnosis ...
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