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Ion channels are located within the membrane of all excitable cells, [ 3] and of many intracellular organelles. They are often described as narrow, water-filled tunnels that allow only ions of a certain size and/or charge to pass through. This characteristic is called selective permeability.
Ion I. Agârbiceanu. Ion I. Agârbiceanu (6 January 1907 – 9 March 1971) was a Romanian physicist born in Bucium, Alba County in Transylvania. He was the son of the writer and Greek-Catholic priest Ion Agârbiceanu and his wife Maria. [1]
Ion Agârbiceanu (first name also Ioan, last name also Agărbiceanu and Agîrbiceanu; 12 September 1882 – 28 May 1963) was an Austro-Hungarian -born Romanian writer, journalist, politician, theologian and Greek-Catholic priest. Born among the Romanian peasant class of Transylvania, he was originally an Orthodox, but chose to embrace Eastern ...
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Ion Barbu ( Romanian pronunciation: [iˈon ˈbarbu], pen name of Dan Barbilian; 18 March 1895 –11 August 1961) was a Romanian mathematician and poet. His name is associated with the Mathematics Subject Classification number 51C05, which is a major posthumous recognition reserved only to pioneers of investigations in an area of mathematical ...
Channelopathies are a group of diseases caused by the dysfunction of ion channel subunits or their interacting proteins. These diseases can be inherited or acquired by other disorders, drugs, or toxins. Mutations in genes encoding ion channels, which impair channel function, are the most common cause of channelopathies. [ 1]
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Voltage-gated ion channels have a crucial role in excitable cells such as neuronal and muscle tissues, allowing a rapid and co-ordinated depolarization in response to triggering voltage change. Found along the axon and at the synapse, voltage-gated ion channels directionally propagate electrical signals. Voltage-gated ion-channels are usually ...