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Salicin is produced in (and named after) willow (Salix) bark. It is a biosynthetic precursor to salicylaldehyde. [4] Salicin hydrolyses into β-d-glucose and salicyl alcohol (saligenin). Salicyl alcohol can be oxidized into salicylaldehyde and salicylate, both biologically and industrially.
Bartram's 1998 Encyclopedia of Herbal Medicine [7] is perhaps typical when it states, 'in 1838 chemists identified salicylic acid in the bark of White Willow. After many years, it was synthesised as acetylsalicylic acid, now known as aspirin.' It goes on to claim that willow extract has the same medical properties as aspirin, which is incorrect.
Willow bark extract became recognized for its specific effects on fever, pain, and inflammation in the mid-eighteenth century [72] after the Rev Edward Stone of Chipping Norton, Oxfordshire, noticed that the bitter taste of willow bark resembled the taste of the bark of the cinchona tree, known as "Peruvian bark", which was used successfully in ...
The bark of white willow contains salicin, which is a chemical similar to aspirin (acetylsalicylic acid). It is thought to be responsible for the pain-relieving and anti-inflammatory effects of the herb. In 1829, salicin was used to develop aspirin. White willow appears to be slower than aspirin to bring pain relief, but the analgesia may last ...
William Turner, in 1597, repeated this, saying that willow bark, "being burnt to ashes, and steeped in vinegar, takes away corns and other like risings in the feet and toes". [31] Some of these cures may describe the action of salicylic acid, which can be derived from the salicin present in willow. It is, however, a modern myth that Hippocrates ...
One commonly known medicinal benefit from the willow tree is the use of its bark. Alaska Natives and other Native American tribes have used the bark from the Willow tree as a pain killer. In fact, the bark does contain acetylsalicylic acid which is now called aspirin and has been commercialized as an over the counter pain killer. [7]
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