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A phase-gate process (also referred to as a waterfall process) is a project management technique in which an initiative or project (e.g., new product development, software development, process improvement, business change) is divided into distinct stages or phases, separated by decision points (known as gates).
Come up with ideas [1] Land and expand To sell a small solution and then grow it within the client's environment Make hay Productive or successful in a short time [1] Moving forward Making progress on an idea or scheme Move the goal posts Change the criteria for success [1] Pick the low-hanging fruit Go (initially) for the easiest options [1]
The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage, which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region.
The waterfall model is the earliest Systems Development Life Cycle approach used in software development. [ 3 ] The waterfall development model originated in the manufacturing and construction industries, [ citation needed ] where the highly structured physical environments meant that design changes became prohibitively expensive much sooner in ...
Waterfall model, in project management for business and software Cash flow waterfall , a securitization arrangement in finance Distribution waterfall , the process by which returned capital is distributed in private equity and real estate funds
In the deal-by-deal waterfall, the bad performances of a single company do not leak over the performances of the other companies. To mitigate the effect of a deal-by-deal waterfall and to make it more attractive to LPs, private equity funds using an American waterfall may include a clawback clause in their LPAs. [5]
Native GLP-1 is a peptide hormone with a half-life of two minutes because it is rapidly cleared by the enzyme dipeptidyl peptidase-4. [29] As a result, different GLP-1 agonist drugs are modified in various ways to extend the half-life, resulting in drugs that can be dosed multiple times per day, daily, weekly, or less often. [29]
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