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Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. [1] Signs and symptoms may include vomiting , abdominal pain , deep gasping breathing , increased urination , weakness, confusion and occasionally loss of consciousness . [ 1 ]
The glucose clamp technique was developed by University of Texas (UT) School of Medicine Professors DeFronzo, Andres and Tobin in 1979. [2] It has since been the gold standard for pharmacodynamic studies in diabetes drug development and diagnostics evaluation. [3]
Ketoacidosis is a metabolic state caused by uncontrolled production of ketone bodies that cause a metabolic acidosis.While ketosis refers to any elevation of blood ketones, ketoacidosis is a specific pathologic condition that results in changes in blood pH and requires medical attention.
If the patient is known to have diabetes, the diagnosis of diabetic ketoacidosis is usually suspected from the appearance and a history of 1–2 days of vomiting. The diagnosis is confirmed when the usual blood chemistries in the emergency department reveal a high blood sugar level and severe metabolic acidosis.
Kussmaul breathing is a deep and labored breathing pattern often associated with severe metabolic acidosis, particularly diabetic ketoacidosis (DKA) but also kidney failure. It is a form of hyperventilation , which is any breathing pattern that reduces carbon dioxide in the blood due to increased rate or depth of respiration.
Unified Diagnostic Services (UDS) is a diagnostic communication protocol used in electronic control units (ECUs) within automotive electronics, which is specified in the ISO 14229-1. [1] It is derived from ISO 14230-3 and the now obsolete ISO 15765-3 (Diagnostic Communication over Controller Area Network (DoCAN) [2]). 'Unified' in this context ...
In partnership with the clinical services provided through the VCU Medical Center, the Hunter Holmes McGuire VA Medical Center (VAMC), Sheltering Arms Rehabilitation Programs, VCU Children’s Hospital of Richmond, the U.S. Navy, the U.S. Marine Corps and other affiliated programs, CERSE has brought together researchers, clinicians ...
Children's Hospital of Richmond at VCU (CHoR) is a nationally ranked pediatric acute care children's hospital located within VCU Medical Center in Richmond, Virginia. The hospital has 144 pediatric beds. It is affiliated with The Virginia Commonwealth University School of Medicine, [1] and is a member of VCU Health. The hospital provides ...