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Cancer Cytopathology is a monthly peer-reviewed scientific journal which covers practice of cytopathology and its related oncology-based disciplines. It is one of three official journals of the American Cancer Society and is published by Wiley-Blackwell on behalf of the society. The current editor-in-chief is William C. Faquin.
If the measurable disease is restricted to a solitary lesion, its neoplastic nature should be confirmed by cytology/histology. Measurable lesions – lesions that can be accurately measured in at least one dimension with longest diameter ≥20 mm using conventional techniques or ≥10 mm by spiral CT scan .
The Bethesda system (TBS), officially called The Bethesda System for Reporting Cervical Cytology, is a system for reporting cervical or vaginal cytologic diagnoses, [1] used for reporting Pap smear results. It was introduced in 1988 [2] and revised in 1991, [3] 2001, [1] [4] [5] and 2014. [6]
Grading in cancer is distinguished from staging, which is a measure of the extent to which the cancer has spread. Pathology grading systems classify the microscopic cell appearance abnormality and deviations in their rate of growth with the goal of predicting developments at tissue level (see also the 4 major histological changes in dysplasia).
Individual states regulate the licensure of cytotechnologists, usually following American Society of Cytopathology (ASC) guidelines. [8] Other countries have their own versions of the ASCT, including the British Association of Cytopathology (BAC) in the UK [9] and the European Federation of Cytology Societies (EFCS) in the EU. [10]
Cytopathology is frequently, less precisely, called "cytology", which means "the study of cells". [2] Cytopathology is commonly used to investigate diseases involving a wide range of body sites, often to aid in the diagnosis of cancer but also in the diagnosis of some infectious diseases and other inflammatory conditions. [3]
Cervical cancer screening is a medical screening test designed to identify risk of cervical cancer. Cervical screening may involve looking for viral DNA, and/or to identify abnormal, potentially precancerous cells within the cervix as well as cells that have progressed to early stages of cervical cancer .
Cytopathology is generally used on samples of free cells or tissue fragments (in contrast to histopathology, which studies whole tissues) and cytopathologic tests are sometimes called smear tests because the samples may be smeared across a glass microscope slide for subsequent staining and microscopic examination.