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General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
Neurosyphilis is the infection of the central nervous system by Treponema pallidum, the bacterium that causes the sexually transmitted infection syphilis.In the era of modern antibiotics, the majority of neurosyphilis cases have been reported in HIV-infected patients.
Tabes dorsalis is caused by demyelination by advanced syphilis infection (tertiary syphilis) when the primary infection by the causative spirochete bacterium, Treponema pallidum, is left untreated for an extended period of time (past the point of blood infection by the organism). [3]
Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum , a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if not treated ...
Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
The term "crazy" (from Middle English meaning cracked) and insane (from Latin insanus meaning unhealthy) came to mean mental disorder in this period. The term "lunacy", long used to refer to periodic disturbance or epilepsy, came to be synonymous with insanity. "Madness", long in use in root form since at least the early centuries AD, and ...
The history of syphilis has been well studied, but the exact origin of the disease was the source of debate until archaeological and genetic evidence showed conclusively it originated in the Americas.
Cause of death disputed, but syphilis or mercury poisoning from syphilis treatment are leading theories. Franz Schubert (1797–1828), German composer Cause of death disputed, but symptoms match to mercury poisoning from syphilis treatment. [10] Robert Schumann (1810–1856), German composer Acquired syphilis from a prostitute in the age of 21 ...