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The prevalence of childhood asthma in the United States has increased since 1980, especially in younger children. Rates of asthma have increased significantly between the 1960s and 2008 [9] [10] with it being recognized as a major public health problem since the 1970s. [5] Some 9% of US children had asthma in 2001, compared with just 3.6% in 1980.
The fundamental problem in asthma appears to be immunological: young children in the early stages of asthma show signs of excessive inflammation in their airways. Epidemiological findings give clues as to the pathogenesis : the incidence of asthma seems to be increasing worldwide, and asthma is now very much more common in affluent countries.
[9] [10] Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. [3] These may occur a few times a day or a few times per week. [4] Depending on the person, asthma symptoms may become worse at night or with exercise. [4] Asthma is thought to be caused by a combination of genetic and environmental factors. [3]
Smoking by either parent, particularly by the mother, increases the risk of asthma in children. The outlook for early childhood asthma is less favourable in smoking households. Children with asthma who are exposed to smoking in the home generally have more severe disease. Many adults with asthma identify ETS as a trigger for their symptoms.
As a result, inflammation and associated healing process leads to scar formation and tissue remodelling, which are symptoms that can be found in almost all asthmatics patients. Thus, asthma is a chronic inflammatory disorder of the airways. Asthma is divided into two subgroups: atopic (extrinsic) and non-atopic (intrinsic).
The cause for acute severe asthma attacks is still unknown and experts are also unsure of why it developed and why it does not respond to typical asthma treatments. [7] [medical citation needed] Not seeing a doctor regularly, therefore asthma is not under good control; Coming in contact with asthma triggers; Allergies or severe allergic reactions
Asthma triggers are factors or stimuli that provoke the exacerbation of asthma symptoms or increase the degree of airflow disruption, which can lead to an asthma attack. [1] An asthma attack is characterized by an obstruction of the airway , hypersecretion of mucus and bronchoconstriction due to the contraction of smooth muscles around the ...
AERD affects an estimated 0.3–0.9% of the general population in the US, including around 7% of all asthmatics, about 14% of adults with severe asthma, and ~5-10% of patients with adult onset asthma. [2] [3] [8] AERD is uncommon among children, with around 6% of patients, predominantly female, reporting disease onset during childhood. [9]
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