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Phenyl-2-nitropropene is used in the pharmaceutical industry to manufacture the drug Adderall, an amphetamine mixture used to treat ADHD and narcolepsy. P2NP and other similar nitrostyrenes are also employed in the clandestine manufacture of drugs of the amphetamine class, and are listed as drug precursors in many countries. [7] [8] [9]
During these years, the drug Adderall was identical to the most recent formulation of Obetrol, except that the inscription on the pills was changed to "AD". [ citation needed ] Sometime after 2000, Shire closed the Rexar manufacturing facility, discontinued immediate-release Adderall and outsourced Adderall XR (extended-release) to a ...
Adderall and Mydayis [11] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [13]
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Levoamphetamine [note 1] is a stimulant medication which is used in the treatment of certain medical conditions. [10] It was previously marketed by itself under the brand name Cydril, but is now available only in combination with dextroamphetamine in varying ratios under brand names like Adderall and Evekeo.
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Lisdexamfetamine, its salts, isomers, and salts of its isomers [20] 2125 depressant Amobarbital [21] 2550 depressant Glutethimide [22] 2270 depressant Pentobarbital [21] 7471 depressant Phencyclidine [23] 2315 depressant Secobarbital [21] 7379 hallucinogen Nabilone [24] 7365 hallucinogen Dronabinol oral solution [25] 8501 precursor ...
On 20 June 2014, Shire rejected a takeover attempt by AbbVie. AbbVie offered £46.11 per share (£27.3 billion or $46.5 billion in total). [30] On 8 July, the offer was increased to $51.5 billion. [31] On 18 July, it was announced that AbbVie would acquire Shire for $54.8 billion. [32]
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