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The first injection had an apparent impurity which was the likely cause for the allergic reaction he displayed. After a refined process was developed by James Collip to improve the canine pancreas extract, the second dosage was successfully delivered to the young patient 12 days after the first.
Ayurvedic physicians (5th/6th century BC) first noted the sweet taste of diabetic urine, and called the condition madhumeha ("honey urine"). The term diabetes traces back to Demetrius of Apamea (1st century BC). For a long time, the condition was described and treated in traditional Chinese medicine as xiāo kě (消渴; "wasting-thirst
Phenformin (DBI) was used from 1960s through 1980s, but was withdrawn due to lactic acidosis risk. [11] Buformin also was withdrawn due to lactic acidosis risk. [12] Metformin is a first-line medication used for treatment of type 2 diabetes.
Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [85] [86] This is a chronology of key milestones in the history of the medical use of insulin. For more details on the discovery, extraction, purification, clinical use, and synthesis of insulin, see Insulin
There is also inhaled insulin that can be used in adults with diabetes. [33] There are several types of insulin that are commonly used in medical practice, with varying times of onset and duration of action. [32] - Rapid acting (i.e. insulin lispro) with onset in 15 minutes and duration of about 4 hrs.
Elliott Proctor Joslin (June 6, 1869 – January 28, 1962) was the first medical doctor in the United States to specialize in diabetes and was the founder of the present-day Joslin Diabetes Center in Boston, Massachusetts.
insulin-dependent diabetes mellitus (now called diabetes mellitus type 1) IDL: intermediate-density lipoprotein: IDP: infectious disease precautions: IE: infective endocarditis: IF: immunofluorescence: IFG: impaired fasting glycaemia: Ig: immunoglobulin: IgA: immunoglobulin A: IgAV: IgA vasculitis (formerly known as Henoch–Schönlein purpura ...
Ancient Greek physician Aretaeus of Cappadocia (fl. in the first century CE) used that word, with the intended meaning "excessive discharge of urine", as the name for the disease. [ 26 ] [ 27 ] Ultimately, the word comes from Greek διαβαίνειν ( diabainein ), meaning "to pass through", [ 25 ] which is composed of δια - ( dia ...