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Early neurosyphilis often has no clinical symptoms. Meningitis is the most-common neurological presentation in early syphilis, typically arising within one year of initial infection. [6] Symptoms of syphilitic meningitis are similar to other forms of meningitis, including headache, neck stiffness, photophobia, confusion, nausea, and vomiting. [7]
Common symptoms that develop over the first couple of years of life include enlargement of the liver and spleen (70%), rash (70%), fever (40%), neurosyphilis (20%), and lung inflammation (20%). [7] If untreated, late congenital syphilis may occur in 40%, including saddle nose deformation, Higouménakis' sign , saber shin , or Clutton's joints ...
Pleocytosis, raised CSF protein level and positive CSF serology suggest neurosyphilis. [31] CSF VDRL is 50-90% specific for neurosyphilis. [18] 60% of newborns with congenital syphilis also have neurosyphilis. [18] Non-treponemal titers should be monitored in the newborns every 2-3 months to ensure an adequate response to treatment. [18]
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
A study called "Are trends in HIV, gonorrhea, and syphilis worsening in western Europe?" in a journal of medicine called BMJ outlines the data collected from 1995 to 2000 on sexually transmitted infections throughout western Europe. As with Russia and China there was a big decline in syphilis before 1980 but a big resurgence during the 1990s. [32]
Etiquette in Society, in Business, in Politics and at Home by Emily Post, published in 1922, contained suggestions for wedding anniversary gifts for 1, 5, 10, 15, 20, 25, 50, and 75 years. [12] Wedding anniversary gift suggestions for other years were added in later editions and publications; they now comprise what is referred to as the ...
Sheng nu: A derogatory Chinese slang term loosely translating to "leftover women", used to describe unmarried older women.(see "Spinster" below) Silver fox: A sexually-attractive or promiscuous older person, typically a woman. (see "cougar" above) Spinster: A woman who, in her own culture, is single beyond the age at which most people get married.
The history of syphilis has been well studied, but the exact origin of the disease was the source of debate until archaeological and genetic evidence showed conclusively it originated in the Americas.