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An autophagosome is a spherical structure with double layer membranes. [2] It is the key structure in macroautophagy , the intracellular degradation system for cytoplasmic contents (e.g., abnormal intracellular proteins , excess or damaged organelles , invading microorganisms).
The completed autophagosome then fuses with a lysosome through the actions of multiple proteins, including SNAREs [72] [73] and UVRAG. [74] Following the fusion LC3 is retained on the vesicle's inner side and degraded along with the cargo, while the LC3 molecules attached to the outer side are cleaved off by Atg4 and recycled. [75]
This chart provides audio examples for phonetic vowel symbols. The symbols shown include those in the International Phonetic Alphabet (IPA) and added material. The chart is based on the official IPA vowel chart. [1] The International Phonetic Alphabet is an alphabetic system of phonetic notation based primarily on the Latin alphabet.
The following is the chart of the International Phonetic Alphabet, a standardized system of phonetic symbols devised and maintained by the International Phonetic Association. It is not a complete list of all possible speech sounds in the world's languages, only those about which stand-alone articles exist in this encyclopedia.
The following are the non-pulmonic consonants.They are sounds whose airflow is not dependent on the lungs. These include clicks (found in the Khoisan languages and some neighboring Bantu languages of Africa), implosives (found in languages such as Sindhi, Hausa, Swahili and Vietnamese), and ejectives (found in many Amerindian and Caucasian languages).
In the vowels chart, a separate phonetic value is given for each major dialect, alongside the words used to name their corresponding lexical sets. The diaphonemes for the lexical sets given here are based on RP and General American; they are not sufficient to express all of the distinctions found in other dialects, such as Australian English.
Before then, the pronunciation of Latin in church was the same as the pronunciation of Latin in other fields and tended to reflect the sound values associated with the nationality and native language of the speaker. [66] Other ecclesiastical pronunciations are still in use, especially outside the Catholic Church.
The charts below show the way in which the IPA represents Inuktitut pronunciations in Wikipedia articles. [1] For a guide to adding IPA characters to Wikipedia articles, see Template:IPA and Wikipedia:Manual of Style/Pronunciation § Entering IPA characters.