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  2. Autophagosome - Wikipedia

    en.wikipedia.org/wiki/Autophagosome

    The initial step of autophagosome formation of an omegasome on the endoplasmic reticulum, followed by of elongation of structures called phagophores. [5] The formation of autophagosomes is controlled by Atg genes through Atg12-Atg5 and LC3 complexes. The conjugate of Atg12-Atg5 also interacts with Atg16 to form larger complexes.

  3. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    In this system, the sex of an individual usually is determined by a pair of sex chromosomes. Typically, females have two of the same kind of sex chromosome (XX), and are called the homogametic sex. Males typically have two different kinds of sex chromosomes (XY), and are called the heterogametic sex. [1]

  4. Sex-determination system - Wikipedia

    en.wikipedia.org/wiki/Sex-determination_system

    No genes are shared between the avian ZW and mammal XY chromosomes [26] and the chicken Z chromosome is similar to the human autosomal chromosome 9, rather than X or Y. This suggests not that the ZW and XY sex-determination systems share an origin but that the sex chromosomes are derived from autosomal chromosomes of the common ancestor of ...

  5. Major histocompatibility complex and sexual selection

    en.wikipedia.org/wiki/Major_histocompatibility...

    These genes have maintained an unusually high level of allelic diversity throughout time and throughout different populations. This means that for each MHC gene, many alleles (or gene variants) consistently exist within the population, and many individuals are heterozygous at MHC loci (meaning they possess two different alleles for a given gene ...

  6. Sex chromosome - Wikipedia

    en.wikipedia.org/wiki/Sex_chromosome

    It is caused by a change in a gene called FMR1. A small part of the gene code is repeated on a fragile area of the X chromosome. The more repeats, the more likely there is to be a problem. Males and females can both be affected, but because males have only one X chromosome, a single fragile X is likely to affect them more.

  7. Sex differences in humans - Wikipedia

    en.wikipedia.org/wiki/Sex_differences_in_humans

    Females normally have two X chromosomes while males typically have an X and a Y chromosome. The X chromosome is more active and encodes more information than the Y chromosome, which has been shown to affect behavior. [14] Genetic researchers theorize that the X chromosome may contain a gene influencing social behaviours. [15] [better source needed]

  8. MAP1LC3B - Wikipedia

    en.wikipedia.org/wiki/MAP1LC3B

    Microtubule-associated proteins 1A/1B light chain 3B (hereafter referred to as LC3) is a protein that in humans is encoded by the MAP1LC3B gene. [5] LC3 is a central protein in the autophagy pathway where it functions in autophagy substrate selection and autophagosome biogenesis. LC3 is the most widely used marker of autophagosomes. [6]

  9. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    X-linked genes are found on the sex X chromosome. X-linked genes just like autosomal genes have both dominant and recessive types. Recessive X-linked disorders are rarely seen in females and usually only affect males. This is because males inherit their X chromosome and all X-linked genes will be inherited from the maternal side.

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