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US 421 enters the Bluegrass State running 272.4 miles (438.4 km) from the Pennington Gap area in Virginia into Harlan County. For the distance between the Virginia state line and closer to Hal Rogers Parkway, it is a major north–south two-lane highway.
U.S. Route 421 (US 421) is part of the United States Numbered Highway System that runs from Fort Fisher, North Carolina to Michigan City, Indiana.In the U.S. state of North Carolina, US 421 travels 328 miles (528 km) from its southern terminus at Fort Fisher to the Tennessee state line near the community of Zionville, North Carolina.
Interstate 85 (I-85) is a part of the Interstate Highway System that runs 666.05 miles (1,071.90 km) from Montgomery, Alabama, to Petersburg, Virginia.In the U.S. state of North Carolina, I-85 crosses the entire state from southwest to northeast (though is signed north–south), at the South Carolina state line near Grover to the Virginia state line near Wise.
US 15/US 501 travel concurrently to Durham. US 1 in Aberdeen. The highways travel concurrently through the city. US 1 south of Sanford. The highways travel concurrently to Sanford. US 421 in Sanford US 64 in Pittsboro I-40 in Durham I-85 / US 70 in Durham. I-85/US 15 travel concurrently to Dutchville Township. US 15/US 70 travel concurrently ...
Lee County is a county located in the U.S. state of North Carolina.As of the 2020 census, the population was 63,285. [1] The county seat is Sanford. [2]Lee County comprises the Sanford, NC Micropolitan Statistical Area, which is a part of the Raleigh-Durham-Cary, NC Combined Statistical Area, which had an estimated population of 2,368,947 in 2023.
U.S. Route 421 Business (US 421 Bus) is a 9.9-mile (15.9 km) multi-lane business loop along Horner Boulevard, through downtown Sanford.Approved by AASHTO on May 3, 2013, its official establishment is dependent on the completion of the Sanford bypass, which mainline US 421 will be rerouted along, sharing with already established NC 87 Bypass.
US 15/US 501 turns left in Durham. From the South Carolina state line, US 15 is in concurrency with US 401 to Laurinburg.Merging with US 501, it becomes what is known as "15-501" ("Fifteen Five-o-one"), a concurrency that extends for 106 miles (171 km) across central North Carolina; US 15 also the dominant partner, using its milemarkers along the route.
Sanford is located in southwestern Hutchinson County at the intersection of Ranch Roads 687 and 1319. It is 1 mile (1.6 km) southeast of the Sanford Dam on the Canadian River , forming Lake Meredith , and it is 11 miles (18 km) northwest of Borger , the county seat .
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