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Natural Cycle IVF is in vitro fertilisation (IVF) using either of the following procedures: IVF without the use any ovarian hyperstimulation drugs. [1] IVF using an ovarian hyperstimulation protocol with a GnRH antagonist for ovulation suppression, generally with gonadotropins as well. [2] This procedure can be called modified natural cycle-IVF ...
The addition of estrogen or hCG as adjunctives to progesterone do not appear to affect outcomes pregnancy rate and live birth rate in IVF. [1] In fact, luteal support with human chorionic gonadotropin (hCG) alone or as a supplement to progesterone has been associated with a higher risk of ovarian hyperstimulation syndrome (OHSS). [2]
In vitro fertilisation (IVF) is a process of fertilisation in which an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating a woman's ovulatory process, then removing an ovum or ova (egg or eggs) from her ovaries and enabling a man's sperm to fertilise them in a culture medium in a laboratory.
Converting the protocol to IVF treatment with embryo transfer of up to two embryos only. [26] Selective fetal reduction. This alternative confers a high risk of complications. [26] Proceeding with any multiple pregnancy without fetal reduction, with the ensuing risk of complications. This alternative is not recommended. [26]
The only progestogens currently used during pregnancy (e.g., for luteal support in IVF protocols or for prevention of preterm birth in pregnant women with a history of at least one spontaneous preterm birth) are: progesterone, hydroxyprogesterone caproate, dydrogesterone, and allylestrenol. [6]
In 2004, of the people younger than 35 who gave birth with the help of IVF, 32.7% delivered twins, and 4.9% delivered triplets, according to doctors at the Washington University School of Medicine ...
For other stimulation protocols, the evidence around pretreatment with combined oral contraceptives and progesterone only is uncertain. [23] Findings are conflicting, but metformin treatment as a complement in IVF cycles may reduce the risk of ovarian hyperstimulation syndrome and increase live birth rates. [24]
As a breakthrough, hMG/hCG protocols for pre-IVF treatment were introduced. [59] The first recombinant human follicle-stimulating hormone (r-hFSH) received EU approval in 1995, followed by the approval of recombinant human luteinizing hormone (rhLH) and recombinant human chorionic gonadotropin (rhCG) in 2000. [59]
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