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  2. Aspartate transaminase - Wikipedia

    en.wikipedia.org/wiki/Aspartate_transaminase

    Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954.

  3. GOT1 - Wikipedia

    en.wikipedia.org/wiki/GOT1

    Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [6]

  4. Transaminase - Wikipedia

    en.wikipedia.org/wiki/Transaminase

    Two important transaminase enzymes are aspartate transaminase (AST), also known as serum glutamic oxaloacetic transaminase (SGOT); and alanine transaminase (ALT), also called alanine aminotransferase (ALAT) or serum glutamate-pyruvate transaminase (SGPT

  5. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Also called serum glutamic pyruvic transaminase ... [5]) Female: 6 [55] 34 [55] IU/L: Also called serum glutamic oxaloacetic transaminase (SGOT) ... Serum: Age > 1 ...

  6. GOT2 - Wikipedia

    en.wikipedia.org/wiki/GOT2

    Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively.

  7. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    Alanine transaminase is one of the two transaminases measured (Aspartate transaminase is the other). In medicine , the presence of elevated transaminases , commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction.

  8. Glutaminolysis - Wikipedia

    en.wikipedia.org/wiki/Glutaminolysis

    glutamate oxaloacetate transaminase (GOT), also called aspartate transaminase (AST), EC 2.6.1.1 (component of the malate aspartate shuttle) Recruited reaction steps of the citric acid cycle and malate aspartate shuttle

  9. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    The liver transaminases aspartate transaminase (AST or SGOT) and alanine transaminase (ALT or SGPT) are useful biomarkers of liver injury in a patient with some degree of intact liver function. [2] [3] [4] Most liver diseases cause only mild symptoms initially, but these diseases must be detected early. Hepatic (liver) involvement in some ...