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Manfred Joshua Sakel (June 6, 1900 – December 2, 1957) was an Austrian-Jewish (later Austrian-American) neurophysiologist and psychiatrist, credited with developing insulin shock therapy in 1927. Biography
In 1927, Sakel, who had recently qualified as a medical doctor in Vienna and was working in a psychiatric clinic in Berlin, began to use low (sub-coma) doses of insulin to treat drug addicts and psychopaths, and when one of the patients experienced improved mental clarity after having slipped into an accidental coma, Sakel reasoned the treatment might work for mentally ill patients. [3]
Insulin shock therapy was discontinued due to critical concerns over its safety and effectiveness. This method, which induced comas in patients through insulin injections, resulted in severe adverse effects, including hypoglycemic episodes, seizures , obesity , and in some cases, irreversible brain damage that was mistakenly regarded as ...
A 71-year-old diabetic woman was left “howling in pain” before she died after she stopped taking insulin at a workshop run by an alternative healer who she described as a “messenger sent by ...
Ohio, Wisconsin: 1978–1991: 16: Known as the "Milwaukee Cannibal" [16] David Van Dyke: Milwaukee 1979–1980 6 Burglar who murdered people after tricking them into letting him into their homes [17] Lorenzo Fayne: Wisconsin, Illinois: 1989–1993: 6: Serial killer and rapist who murdered one woman and five children in the states of Wisconsin ...
Paul McNairney, 39, died after the Omnipod delivered four days’ worth of insulin in less than an hour, according to data obtained by a legal firm. Widower calls on health boards to ban insulin ...
Glucagon is a hormone that rapidly counters the metabolic effects of insulin in the liver, causing glycogenolysis and release of glucose into the blood. It can raise the glucose by 30–100 mg/dL within minutes in any form of hypoglycemia caused by insulin excess (including all types of diabetic hypoglycemia).
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