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Forensic toxicology is a multidisciplinary field that combines the principles of toxicology with expertise in disciplines such as analytical chemistry, pharmacology and clinical chemistry to aid medical or legal investigation of death, poisoning, and drug use. [1]
-do- •Countercurrent chromatography-do- •Countercurrent chromatography-do- Setup for Radioimmunoassay (RIA) previously it was widely used to detect various things in bold fluids like proteins (natural, infective, those produced by the body in reaction to disease, cancer related), tumor markers, hormones, viruses (hepatitis, HIV, etc.), etc.
Forensic toxicology is the discipline that makes use of toxicology and other disciplines such as analytical chemistry, pharmacology and clinical chemistry to aid medical or legal investigation of death, poisoning, and drug use. The primary concern for forensic toxicology is not the legal outcome of the toxicological investigation or the ...
Medical toxicology is a subspecialty of medicine focusing on toxicology and providing the diagnosis, management, and prevention of poisoning and other adverse effects due to medications, occupational and environmental toxicants, and biological agents. [1]
In vitro toxicity testing is the scientific analysis of the toxic effects of chemical substances on cultured bacteria or mammalian cells. [1] In vitro (literally 'in glass') testing methods are employed primarily to identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as ...
Doxorubicin is a very effective anti-cancer drug that causes congestive heart failure while treating tumors. [7] Doxorubicin is an uncoupling agent in that it inhibits proper functioning of complex I of the electron transport chain in mitochondria. It then leads to the production of ROS and the inhibition of ATP production.
The Reinsch test is an initial indicator to detect the presence of one or more of the following heavy metals in a biological sample, and is often used by toxicologists where poisoning by such metals is suspected.
The discipline of evidence-based toxicology (EBT) strives to transparently, consistently, and objectively assess available scientific evidence in order to answer questions in toxicology, [1] the study of the adverse effects of chemical, physical, or biological agents on living organisms and the environment, including the prevention and amelioration of such effects. [2]