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Mavacamten, sold under the brand name Camzyos, is a medication used to treat obstructive hypertrophic cardiomyopathy. [8] [9] Mavacamten is a small-molecule allosteric [10] and cardiac myosin inhibitor. [8] It was developed by MyoKardia, a subsidiary of Bristol Myers Squibb. [11]
Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. [8] The parts of the heart most commonly affected are the interventricular septum and the ventricles . [ 10 ]
Septal myectomy is a cardiac surgery treatment for hypertrophic cardiomyopathy (HCM). [1] The open-heart surgery entails removing a portion of the septum that is obstructing the flow of blood from the left ventricle to the aorta. [2]
Hypertrophic cardiomyopathy doesn’t always need treatment, but doctors often recommend weight loss and may prescribe medications such as: Beta-blockers Calcium-channel blockers
Treatment sometimes involves an implantable defibrillator. Credit - Karsten Eggert—Getty Images. H ypertrophic cardiomyopathy is the most common form of genetic heart disease worldwide ...
Alcohol septal ablation (ASA) is a minimally invasive heart procedure to treat hypertrophic cardiomyopathy (HCM). [1]It is a percutaneous, minimally invasive procedure performed by an interventional cardiologist to relieve symptoms and improve functional status in eligible patients with severely symptomatic HCM who meet strict clinical, anatomic and physiologic selection criteria.
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