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When that happens, blood pressure in the lungs increases, and the heart has to work harder to get blood through those tiny arteries — a process that can eventually tire out the lungs ...
This story was reviewed by Mike Bohl, MD. In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina (chest pain) from heart disease.
Many of these pills work fairly quickly. Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 ...
For a time, the generic was not available in the same dosages as branded Viagra, so using dosages typically required for treating ED required patients to take multiple pills. [95] In 1994, Pfizer filed a patent covering the use of sildenafil to treat erectile dysfunction. [96] This would be marketed as Viagra.
Recreational Viagra use does happen, and while some men see harmless benefits from the active ingredient in the famous “little blue pill,” they’re still taking a significant risk every time ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
It’s important to take caution with ED medication if you have any type of cardiovascular health condition, such as heart disease, congestive heart failure, an irregular heartbeat, hypertension ...
When used with nitrates, Cialis and Viagra can produce a sudden drop in blood pressure levels that may cause dizziness, lightheadedness, fainting and serious cardiovascular events, such as heart ...
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