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Methamphetamine is often used recreationally for its effects as a potent aphrodisiac, euphoriant, and stimulant. [11] It has been further described that "an entire subculture known as party and play is based around methamphetamine use." [11] Gay men belonging to this subculture will typically meet up through internet dating sites to have sex. [11]
Amphetamine type stimulants can be used in the treatment of narcolepsy, a rare neurological disorder where the brain is unable to regulate the sleep-wake mechanism. [17] Amphetamines causes an increase in dopamine release, which is the proposed mechanism for its wake-promoting effect. [18]
Treatment for amphetamines is growing at extremely high rates around the world. [15] Psychostimulants that increase dopamine and mimic the effects of substituted amphetamines, but with lower abuse liability, could theoretically be used as replacement therapy in amphetamine dependence. [8]
[25] [152] When taken orally, 30–54% of the dose is excreted in urine as methamphetamine and 10–23% as amphetamine. [152] Following IV doses, about 45% is excreted as methamphetamine and 7% as amphetamine. [152] The elimination half-life of methamphetamine varies with a range of 5–30 hours, but it is on average 9 to 12 hours in most studies.
MDMA was also found to have effects on blood sugar levels comparable to high doses of ephedrine. Oberlin concluded that the effects of MDMA were not limited to the sympathetic nervous system. Research was stopped "particularly due to a strong price increase of safrylmethylamine", which was still used as an intermediate in methylhydrastinine ...
What Is Adderall? Adderall is a brand name for a medication that contains a combination of dextroamphetamine and amphetamine. Most commonly prescribed for ADHD, Adderall can also be used to treat ...
Amphetamine is a potent central nervous system (CNS) stimulant of the phenethylamine class that is approved for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. [82] Amphetamine is also used off-label as a performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant.
The term PnP is commonly used by gay men [94] [failed verification] and other men who have sex with men (MSM) in North America, while chemsex is more associated with the gay scene in Europe. [95] The drug of choice is typically methamphetamine , known as tina or T, [ 96 ] but other drugs are also used, such as mephedrone , GHB , GBL [ 97 ] and ...