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  2. Urease - Wikipedia

    en.wikipedia.org/wiki/Urease

    In the stomach there is an increase in pH of the mucosal lining as a result of urea hydrolysis, which prevents movement of hydrogen ions between gastric glands and gastric lumen. [20] In addition, the high ammonia concentrations have an effect on intercellular tight junctions increasing permeability and also disrupting the gastric mucous ...

  3. Rapid urease test - Wikipedia

    en.wikipedia.org/wiki/Rapid_urease_test

    Rapid urease test, also known as the CLO test (Campylobacter-like organism test), is a rapid diagnostic test for diagnosis of Helicobacter pylori. [1] The basis of the test is the ability of H. pylori to secrete the urease enzyme, which catalyzes the conversion of urea to ammonia and carbon dioxide .

  4. Helicobacter pylori - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori

    Urease is the most abundant protein, its expression representing about 10% of the total protein weight. [33] H. pylori possesses five major outer membrane protein families. [32] The largest family includes known and putative adhesins. The other four families are porins, iron transporters, flagellum-associated proteins, and proteins of unknown ...

  5. Urea breath test - Wikipedia

    en.wikipedia.org/wiki/Urea_breath_test

    Patients swallow urea labelled with an uncommon isotope, either radioactive carbon-14 (nowadays preferred in many countries) or non-radioactive carbon-13.In the subsequent 10–30 minutes, the detection of isotope-labelled carbon dioxide in exhaled breath indicates that the urea was split; this indicates that urease (the enzyme that H. pylori uses to metabolize urea to produce ammonia) is ...

  6. Timeline of peptic ulcer disease and Helicobacter pylori

    en.wikipedia.org/wiki/Timeline_of_peptic_ulcer...

    Urease 1924 Luck and Seth discover urease in the human stomach, which they believe is naturally occurring. [11] 1925 Hoffman injects a small sample from a human with PUD into a guinea pig, producing ulcers, and isolates a bacterium which he believes caused the ulcers. [12] 1936

  7. 14 Things That Might Be Causing Pain in Your Lower Left Abdomen

    www.aol.com/14-things-might-causing-pain...

    Gastroenteritis, often called the “stomach flu,” is an infection in your stomach and intestines. It causes symptoms like diarrhea, nausea, vomiting, and cramps, notes Dr. Boxer.

  8. Urea - Wikipedia

    en.wikipedia.org/wiki/Urea

    The test detects the characteristic enzyme urease, produced by H. pylori, by a reaction that produces ammonia from urea. This increases the pH (reduces the acidity) of the stomach environment around the bacteria. Similar bacteria species to H. pylori can be identified by the same test in animals such as apes, dogs, and cats (including big cats).

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