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Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. [ 3 ] [ 4 ] Generally it is used together with dietary changes and a statin . [ 5 ]
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
On rare occasions, ezetimibe may cause cholecystitis, pancreatitis, elevation of serum transaminase level and rhabdomyolysis. As hepatic impairment hinders the rate of ezetimibe metabolism by the liver, ezetimibe is not recommended in individuals with moderate or severe hepatic insufficiency due to prolonged systemic exposure to the drug. [ 19 ]
When symptoms grow worse (more on this later), heart failure can cause swelling in the ankles and legs, as well as swollen feet. This is due to edema, which is a fluid accumulation in the body ...
That’s why a leg elevation pillow can be helpful in easing inflammation, lower extremity swelling, leg ulcers, and varicose veins, as well as decreasing the likelihood of blood clots, says ...
The condition is commonly associated with vascular and cardiac changes associated with aging but can be caused by many other conditions, including congestive heart failure, kidney failure, liver cirrhosis, portal hypertension, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, a compromised lymphatic system or merely long periods of time sitting or standing ...
Both strengths can work well for everyday use, athletic recovery, travel, and mild swelling and aches. However, anything above 20 mmHg is prescribed by doctors for specific conditions.
Swelling of the limb may cause inhibited flow by increased pressure, and in the legs (but very rarely in the arms), this may indicate a fasciotomy, opening up all four leg compartments. [8] Because of the high recurrence rates of thromboembolism, it is necessary to administer anticoagulant therapy as well. [11]