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Currently, the only intervention proven to reduce ovarian cancer risk is bilateral salpingo-oophorectomy (BSO) at age 35–40 for BRCA1 carriers or age 40–45 for BRCA2, which has been shown to decrease incidence by 80-96%. During BSO both ovaries and both fallopian tubes are removed in one operation.
In medicine, salpingo-oophorectomy is the removal of an ovary and its fallopian tube. [1] [2] This procedure is most frequently associated with prophylactic surgery in response to the discovery of a BRCA mutation, particularly those of the normally tumor suppressing BRCA1 gene (or, with a statistically lower negative impact, those of the tumour suppressing BRCA2 gene), which can increase the ...
Prophylactic oophorectomy is the removal of the ovaries and is either done as a planned response to the genetic risk of ovarian or breast cancer, especially among women whom have a hereditary family history of ovarian cancer, have the BRCA1 or BRCA2 mutations, [17] or have developed breast cancer in the past. [18]
Most bilateral oophorectomies (63%) are performed without any medical indication, and most (87%) are performed together with a hysterectomy. [9] Conversely, unilateral oophorectomy is commonly performed for a medical indication (73%; cyst, endometriosis, benign tumor, inflammation, etc.) and less commonly in conjunction with hysterectomy (61%).
What Is a Hysterectomy? A hysterectomy is a fairly common surgical procedure wherein the uterus is removed. According to the Centers for Disease Prevention and Control (CDC), 14.6% of women aged ...
Bilateral salpingo-oophorectomy (BSO) is the removal of both ovaries and fallopian tubes. According to the ACOG, symptomatic uterine leiomyomas are the most common indication for hysterectomy in the US, followed by abnormal uterine bleeding, endometriosis and prolapse. [ 5 ]
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