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The nuclear lamina consists of two components, lamins and nuclear lamin-associated membrane proteins. The lamins are type V intermediate filaments which can be categorized as either A-type (lamin A, C) or B-type (lamin B 1, B 2) according to homology of their DNA sequences, biochemical properties and cellular localization during the cell cycle.
In neuroanatomy, the lateral geniculate nucleus (LGN; also called the lateral geniculate body or lateral geniculate complex) is a structure in the thalamus and a key component of the mammalian visual pathway.
During mitosis, lamins are phosphorylated by Mitosis-Promoting Factor (MPF), which drives the disassembly of the lamina and the nuclear envelope. This allows chromatin to condense and the DNA to be replicated. After chromosome segregation, dephosphorylation of nuclear lamins by a phosphatase promotes reassembly of the nuclear envelope.
In a coronal section through the middle of the lentiform nucleus, two medullary laminae are seen dividing it into three parts. The lateral and largest part is of a reddish color, and is known as the putamen, while the medial and intermediate are of a yellowish tint, and together constitute the globus pallidus; all three are marked by fine radiating white fibers, which are most distinct in the ...
Lamina VII: intermediomedial nucleus, intermediolateral nucleus, posterior thoracic nucleus in the thoracic and upper lumbar region [6] Lamina X: an area of grey matter – the grey commissure surrounding the central canal. This region also serves to connect the anterior and posterior grey columns. [3] Rexed never described this as lamina X but ...
The nuclear envelope is made up of two lipid bilayer membranes, an inner nuclear membrane and an outer nuclear membrane. These membranes are connected to each other by nuclear pores. Two sets of intermediate filaments provide support for the nuclear envelope. An internal network forms the nuclear lamina on the inner nuclear membrane. [7]
Likewise, during the same period, the nuclear lamina is also disassembled, a process regulated by phosphorylation of the lamins by protein kinases such as the CDC2 protein kinase. [66] Towards the end of the cell cycle, the nuclear membrane is reformed, and around the same time, the nuclear lamina are reassembled by dephosphorylating the lamins ...
Within the lamina, fibers turn posteriorly and enter the dorsal side of the thalamus. Therefore, as a result of these various pathways, the neurons of the dentate nucleus are able to traverse all thalamic nuclei, with the exception of those at the midline and anterior nuclear groups. [11] Dentate nucleus axons can be divergent or convergent.