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PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: vitiligo, eczema, psoriasis, graft-versus-host disease, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen.
Side-effects may include itching and redness of the skin due to UVB exposure, and possibly sunburn, if patients do not minimize exposure to natural UV rays during treatment days. Cataracts can frequently develop if the eyes are not protected from UV light exposure.
UV-B treatments for skin conditions such as psoriasis, vitiligo, and atopic dermatitis are administered in very low doses, often lasting only a few minutes or less than a minute when using lamps emitting 290-300 nanometer light. This low dosage does not significantly increase the risk of skin cancer, making UV-B phototherapy a safe treatment ...
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[8] [9] However, Goeckerman therapy is considered safe although use of tar may have the side-effects of contact dermatitis and mild local burning due to tar hypersensitivity. A retrospective study by Stern et al., of 1,373 patients concluded that there was an increase in skin cancers in those receiving repeated Goeckerman treatments compared to ...
Mercury was also used for psoriasis treatment during this time. [134] Sulfur, iodine, and phenol were also commonly used treatments for psoriasis during this era when it was incorrectly believed that psoriasis was an infectious disease. [134] Coal tars were widely used with ultraviolet light irradiation as a topical treatment approach in the ...
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