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Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]
Biologically speaking, any substance, if given in large enough amounts, is poisonous and can cause death. For instance, several kilograms worth of water would constitute a lethal dose. Many substances used as medications—such as fentanyl—have an LD 50 only one order of magnitude greater than the ED50. An alternative classification ...
Endotoxins most commonly refer to the lipopolysaccharide (LPS) or lipooligosaccharide (LOS) that are in the outer plasma membrane of Gram-negative bacteria. The botulinum toxin, which is primarily produced by Clostridium botulinum and less frequently by other Clostridium species, is the most toxic substance known in the world. [1]
The man, however, has since recovered and left the hospital. It's strongly suspected the two were poisoned by aconite, an alkaloid toxin found in the raw roots and flowers of its namesake plant.
The hooded pitohui.The neurotoxin homobatrachotoxin on the birds' skin and feathers causes numbness and tingling on contact.. The following is a list of poisonous animals, which are animals that passively deliver toxins (called poison) to their victims upon contact such as through inhalation, absorption through the skin, or after being ingested.
This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. § 11002). The list can be found as an appendix to 40 CFR 355. [1] Updates as of 2006 can be seen on the Federal Register, 71 FR 47121 (August 16, 2006). [2]
The term "environmental toxin" can sometimes explicitly include synthetic contaminants [26] such as industrial pollutants and other artificially made toxic substances. As this contradicts most formal definitions of the term "toxin", it is important to confirm what the researcher means when encountering the term outside of microbiological contexts.
No animal species is known to be immune to the acute toxic effects of aflatoxins. Adult humans have a high tolerance for aflatoxin exposure and rarely succumb to acute aflatoxicosis, [ 31 ] but children are particularly affected, and their exposure can lead to stunted growth and delayed development, in addition to all the symptoms mentioned below.