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The innate immune system or nonspecific immune system [1] is one of the two main immunity strategies in vertebrates (the other being the adaptive immune system). The innate immune system is an alternate defense strategy and is the dominant immune system response found in plants , fungi , prokaryotes , and invertebrates (see Beyond vertebrates ).
Innate immunity is the first line of defense against cancer. It consists of non-specific immune cells that can recognize and destroy abnormal cells, including cancer cells. Natural killer (NK) cells, dendritic cells, and macrophages are some examples of innate immune cells that can detect and eliminate cancer cells.
Innate immunity, also known as native immunity, is a semi-specific and widely distributed form of immunity. It is defined as the first line of defense against pathogens, representing a critical systemic response to prevent infection and maintain homeostasis, contributing to the activation of an adaptive immune response. [ 4 ]
Non-specific immunity, or innate immunity, is the immune system with which you were born, made up of phagocytes and barriers. Phagocytosis, derived from the Greek words phagein, meaning to eat, kytos or cell, and “osis” meaning process, was first described by Élie Metchnikoff, who won the Nobel Prize 100 years ago. Phagocytosis involves ...
Innate immune defenses are non-specific, meaning these systems respond to pathogens in a generic way. [19] This system does not confer long-lasting immunity against a pathogen. The innate immune system is the dominant system of host defense in most organisms, [ 2 ] and the only one in plants.
Immunology is a branch of biology and medicine [1] that covers the study of immune systems [2] in all organisms.. Immunology charts, measures, and contextualizes the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as autoimmune diseases, hypersensitivities, [3] immune deficiency, [4] and ...
2011 Bruce Beutler (1957-), Jules A. Hoffmann (1941-), "for their discoveries concerning the activation of innate immunity" and Ralph Marvin Steinman (1943-2011)"for his discovery of the dendritic cell and its role in adaptive immunity"
Innate immune memory (trained immunity) is defined as a long-term functional reprogramming of innate immune cells evoked by exogenous or endogenous insults and leading to an altered response towards a second challenge after returning to a non-activated state.