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  2. Aldosterone - Wikipedia

    en.wikipedia.org/wiki/Aldosterone

    Aldosterone release causes sodium and water retention, which causes increased blood volume, and a subsequent increase in blood pressure, which is sensed by the baroreceptors. [39] To maintain normal homeostasis these receptors also detect low blood pressure or low blood volume, causing aldosterone to be released.

  3. Adrenal gland - Wikipedia

    en.wikipedia.org/wiki/Adrenal_gland

    The amount of sodium present in the body affects the extracellular volume, which in turn influences blood pressure. Therefore, the effects of aldosterone in sodium retention are important for the regulation of blood pressure. [28] Glucocorticoids. Cortisol is the main glucocorticoid in humans.

  4. Renin–angiotensin system - Wikipedia

    en.wikipedia.org/wiki/Renin–angiotensin_system

    Angiotensin III increases blood pressure and stimulates aldosterone secretion from the adrenal cortex; it has 100% adrenocortical stimulating activity and 40% vasopressor activity of angiotensin II. Angiotensin IV also has adrenocortical and vasopressor activ vasoconstrictive peptide that causes blood vessels to narrow, resulting in increased ...

  5. Renal physiology - Wikipedia

    en.wikipedia.org/wiki/Renal_physiology

    When renin levels are elevated, the concentrations of angiotensin II and aldosterone increase, leading to increased sodium chloride reabsorption, expansion of the extracellular fluid compartment, and an increase in blood pressure. Conversely, when renin levels are low, angiotensin II and aldosterone levels decrease, contracting the ...

  6. Mineralocorticoid - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid

    The primary endogenous mineralocorticoid is aldosterone, although a number of other endogenous hormones (including progesterone [1] and deoxycorticosterone) have mineralocorticoid function. Aldosterone acts on the kidneys to provide active reabsorption of sodium and an associated passive reabsorption of water, as well as the active secretion of ...

  7. Adrenal insufficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenal_insufficiency

    To confirm inappropriately low cortisol secretion, testing can include baseline morning cortisol level in the blood or morning cortisol level in the saliva. [2] Cortisol levels typically peak in the morning; thus, low values indicate true adrenal insufficiency. [2] Urinary free cortisol can also be measured, but are not necessary for diagnosis. [2]

  8. Renin - Wikipedia

    en.wikipedia.org/wiki/Renin

    Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin-angiotensin-aldosterone system (RAAS)—also known as the renin-angiotensin-aldosterone axis—that increases the volume of extracellular fluid (blood plasma, lymph, and interstitial fluid) and causes arterial ...

  9. Adrenocortical hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocortical_hormone

    Sodium levels also see an increase which results in fluid retention in tissues and elevated blood pressure. In addition to hypersecretion of cortisol , excess androgens are secreted. [ 8 ] In females, increased secretion of androgens , such as testosterone , results in masculinization which may present as facial hair growth and a deepened voice.