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[10] [15] During normal human pregnancy, estrogen production increases progressively and extremely high estrogen levels are attained. [19] Estradiol levels range from 1,000 to 40,000 pg/mL across pregnancy, [20] are on average 25,000 pg/mL at term, and reach levels as high as 75,000 pg/mL in some women. [21
Average number of moderate-to-severe hot flashes per week with placebo and different doses of oral estradiol in menopausal women [40] [41]. Estradiol is used in menopausal hormone therapy to prevent and treat moderate to severe menopausal symptoms such as hot flashes, vaginal dryness and atrophy, and osteoporosis (bone loss). [11]
These help symptoms by replacing the hormones your body isn't making enough of — for instance, estrogen, according to the Cleveland Clinic. When your hormone levels stabilize, your symptoms ...
In the context of the menopause, menopausal hormone therapy (MHT) is the use of estrogen in women without a uterus and estrogen plus progestogen in women who have an intact uterus. [ 81 ] MHT may be reasonable for the treatment of menopausal symptoms, such as hot flashes. [ 82 ]
The most widely used and most effective treatment for many perimenopause and menopause symptoms, including hot flashes and vaginal dryness, is hormone therapy (HT), says Nanette Santoro, M.D ...
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