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  2. Extended-release morphine - Wikipedia

    en.wikipedia.org/wiki/Extended-release_morphine

    Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.

  4. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Morphine: C & M Cocaine: PCP: Space, whack Cocaine: Wine: Coca wine: Ethanol is metabolized into cocaethylene: Cocaine: Quetiapine: Q-ball Codeine: Glutethimide: Pancakes and syrups Combination of glutethimide and codeine cough syrup Codeine: Promethazine: Lean, purple drank, oil Crack cocaine: Fentanyl: Dirty fentanyl, takeover [citation ...

  5. Morphine - Wikipedia

    en.wikipedia.org/wiki/Morphine

    Morphine is highly addictive and prone to abuse. [12] If one's dose is reduced after long-term use, opioid withdrawal symptoms may occur. [12] Caution is advised for the use of morphine during pregnancy or breastfeeding, as it may affect the health of the baby. [12] [2] Morphine was first isolated in 1804 by German pharmacist Friedrich Sertürner.

  6. List of opioids - Wikipedia

    en.wikipedia.org/wiki/List_of_opioids

    Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."

  7. Which diabetes drugs are linked to the lowest depression risk?

    www.aol.com/diabetes-drugs-linked-lowest...

    GLP-1 drugs are linked to a lower risk of depression in people with diabetes, according to a new study. Image credit: Tatsiana Volkava/Getty Images.

  8. Ondansetron - Wikipedia

    en.wikipedia.org/wiki/Ondansetron

    Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...

  9. List of fentanyl analogues - Wikipedia

    en.wikipedia.org/wiki/List_of_fentanyl_analogues

    The weakest compounds such as benzylfentanyl are around the same potency as codeine (i.e. approximately 1/10th the potency of morphine), while the strongest compounds such as carfentanil and ohmefentanil can be over 10,000x more potent than morphine, meaning there is a 100,000-fold variation in potency between the strongest and weakest fentanyl ...